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Shining light on Hemolysis detection

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Hear what your peers say

The GEM Premier 7000 with iQM3* is a breakthrough in blood gas testing—the only blood gas system capable of detecting hemolysis on whole blood samples at the point of care. News outlets are spotlighting its impact, as early adopters report improved patient management and decreased cost of care—making it a vital tool in today’s point-of-care testing environment.

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Multi-Institution Comparison of Whole Blood Potassium Hemolysis Rates

A new publication published in Clinical Biochemistry, reports an overall hemolysis rate of 10% across departments including the emergency department (ED), intensive care unit (ICU), neonatal ICU (NICU), and other inpatient units in four institutions. Samples collected in the ED showed even higher rates, with levels reported as high as 17%.1


"This study demonstrates the importance of hemolysis detection in whole blood specimens and at the POC for improving laboratory quality and patient safety."1

READ THE PAPER IN CLINICAL BIOCHEMISTRY
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Handling Hemolytic Blood Samples from High-Risk Clinical Areas

Published in The Journal of Applied Laboratory Medicine, this special report discusses the importance of in vitro hemolysis as a significant preanalytical error with potential for serious consequences in acute care settings.2 It highlights variability in current practices and emphasizes the need for hemolysis detection in whole blood and provides six recommendations as a call to action to address this significant preanalytical error.

READ THE PAPER IN THE JOURNAL OF APPLIED LABORATORY MEDICINE
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The Ohio State University Experience in the ED

The Ohio State University in Columbus, OH was featured on TV news station, NBC4 Raleigh, highlighting how point-of-care hemolysis detection enhances treatment speed and accuracy, while reducing healthcare costs.3

“I’m very lucky to work at Ohio State, one of the first places in the country to use this type of blood gas analyzer.”3

– Robert Cooper, MD, Clinical Associate Professor of Emergency Medicine, Ohio State University

HEAR WHAT THE OHIO STATE UNIVERSITY CLINICIANS HAVE TO SAY
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University of Kentucky HealthCare Experience in Neonatal Care

UK HealthCare in Lexington, KY was featured in a story on TV news station Spectrum 1, showcasing how hemolysis detection in the NICU enhances diagnostic accuracy, reduces treatment delays, and minimizes the need for repeat samples on a vulnerable patient population.4

"When you’re dealing with premature infants or just babies in general, you are limited to how much blood you can draw. You might need to make clinical decisions and treatment decisions based on that result. If you don’t know that it’s (hemolysis) there, that could go missed and negatively impact the patient.”4

- Robert Maynard, PhD, Assistant Professor of Pathology and Laboratory Medicine, UK College of Medicine

HEAR WHAT UK HEALTHCARE CLINICANS HAVE TO SAY
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New system for hemolysis detection at point of care

Featured in the October 2024 issue of CAP Today, the GEM Premier 7000 with iQM3 is the first blood gas system to detect hemolysis at the point of care.5

“[Hemolysis is] like the elephant in the room. While it's obvious to laboratorians, it is not openly discussed because that would highlight a deficiency.”5

– Alan Wu, PhD, Professor of Laboratory Medicine, University of California San Francisco

READ THE CAP TODAY ARTICLE

Testimonials

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Chris W. Farnsworth, PhD

Associate Professor, Pathology and Immunology

Washington University School of Medicine

Medical Director, Clinical Chemistry, and Point-of-Care Testing

Barnes Jewish Hospital

St Louis, MO

One game-changing breakthrough in 2024 was the emergence of hemolysis detection in whole blood for blood gas testing with the GEM Premier 7000.

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Heather Stieglitz, PhD

Clinical Assistant Professor, Department of Pathology
The 
Ohio State University College of Medicine
Co-Director, Clinical Chemistry and Toxicology

The Ohio State University, Wexner Medical Center
Columbus, OH

Hemolysis is an important preanalytical variable that definitely occurs in blood gas samples at the point of care, and we were not able to detect it before. Werfen’s is the first testing system that allows us to measure for that potential preanalytical variable in these samples.

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GEM, Premier, GEM Premier ChemSTAT, ChemSTAT, GEMweb, iQM, Hemochron, VerifyNow, Avoximeter, and ROTEM are trademarks of Instrumentation Laboratory Company (d.b.a. Werfen) and/or one of its subsidiaries or parent companies and may be registered in the United States Patent and Trademark Office and in other jurisdictions. The Werfen logo is a trademark of Werfen and may be registered in the Patent and Trademark Offices of jurisdictions throughout the world. All other product names, company names, marks, logos, and symbols are trademarks of their respective owners.

©2025 Instrumentation Laboratory. All rights reserved.

*Not available in all countries.

References:

  1. Farnsworth C, Yang J, Maynard R, Stieglitz HM. Multi-institution comparison of whole blood potassium hemolysis rates. Clin Biochem. 2025;138:110955. doi:10.1016/j.clinbiochem.2025.110955. 
  2. Wu AHB, Levy JH, Peacock WF, et al. Handling Hemolytic Blood Samples from High-Risk Clinical Areas: A Call to Action. J Appl Lab Med. 2025;10(5):1347-1361. doi:10.1093/jalm/jfaf082
  3. Bender S. Ohio State hospital detecting blood test errors faster with new technology. NBC4 WCMH-TV, 2025. Accessed November 17, 2025. https://www.nbc4i.com/news/local-news/ohio-state-university/ohio-state-hospital-detecting-blood-test-errors-faster-with-new-technology/#:~:text=The%20hospital%20is%20among%20the,and%20significantly%20reduce%20care%20costs.
  4. Torrellas G. How new blood-analyzing technology benefits NICU babies. Spectrum News 1, 2025. Accessed November 17, 2025. https://spectrumnews1.com/ky/louisville/news/2024/12/17/nicu-technology
  5. Paxton A. New system for hemolysis detection at point of care. CAP Today. Published October 2024. Accessed November 17, 2025. https://www.captodayonline.com/new-system-for-hemolysis-detection-at-point-of-care/?print=pdf

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